The Effect of pH on Sodium Dodecyl Sulphate (SDS) Toxicity Towards Zebrafish (Danio Rerio) Larvae Development

Abstract

SDS is a chemical widely used in cleaning and personal care products like soap. Its use in detergents may harm aquatic ecosystems. This research investigates the effects of pH on SDS toxicity in zebrafish larvae development and observes any phenotypic deformities under different pH conditions. Zebrafish eggs (30 per treatment and control) were exposed to SDS (0.000004%) at pH 5.86 and pH 6.95. The hatching rate (p<0.218), free swim rate (p<0.56), and survival rate (p<0.168) were observed. Results show no significant effects of pH on these rates. Additionally, no significant differences were found in phenotypic deformities (pericardial edema, yolk sac edema, and vertebral bend) under varying pH conditions. However, pericardial and yolk sac edema appeared only in the presence of SDS which resulting in statistically insignificant differences. This study concludes that pH alteration may mask SDS effects on zebrafish larvae development, highlighting its role in controlling pollution.